Enriching chemical space with diversity-oriented synthesis.
Curr Opin Drug Discov Devel
; 9(6): 700-12, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17117681
ABSTRACT
The search for new molecular entities in drug discovery and chemical genetic programs requires the screening of high-quality collections of structurally diverse small molecules. The design and synthesis of such collections remains a major challenge to synthetic chemists. Recent strategies and results are presented in the context of the chemical space being interrogated.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Desenho de Fármacos
/
Técnicas de Química Combinatória
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article