Au(I)-catalyzed cyclization of enynes bearing an olefinic cycle.
J Org Chem
; 71(25): 9366-72, 2006 Dec 08.
Article
em En
| MEDLINE
| ID: mdl-17137363
ABSTRACT
Gold(I)-catalyzed cyclization of enynes containing an olefinic cycle has been studied. The introduction of an olefinic ring instead of a terminal alkene in enynes dramatically increased the yield of the reaction. Enynes having an olefinic cycle were prepared by a rhodium-catalyzed intermolecular [4 + 2] cycloaddition of diynes with butadiene. Consecutive rhodium-catalyzed Diels-Alder/gold(I)-catalyzed cycloisomerization reactions were integrated in a one-pot reaction.
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01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article