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Mechanical properties and biological behavior of carbon nanotube/polycarbosilane composites for implant materials.
Wang, Wei; Watari, Fumio; Omori, Mamoru; Liao, Susan; Zhu, Yuhe; Yokoyama, Atsuro; Uo, Motohiro; Kimura, Hisamichi; Ohkubo, Akira.
Afiliação
  • Wang W; Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan. ww1120@den.hokudai.ac.jp
J Biomed Mater Res B Appl Biomater ; 82(1): 223-30, 2007 Jul.
Article em En | MEDLINE | ID: mdl-17183562
ABSTRACT
Multiwalled carbon nanotube/polycarbosilane (MWCNT/PCS) composites were fabricated by the spark plasma sintering (SPS) method. The MWCNT/PCS composites consisted of MWCNTs and nanosized SiC particles pyrolyzed from PCS and possessing good mechanical properties for bone tissue repair or dental implantation. The MWCNT/PCS composites were implanted in the subcutaneous tissue and femur of rats at 1 and 4 weeks after implantation. Histological investigations showed that there was little inflammatory response in the subcutaneous tissue, and newly formed bone tissue was observed in the femur. These results indicated that the MWCNT/PCS composite had little prophlogistic effect and good osteoconductivity. The study suggested the possibility that the MWCNT/PCS composite could be a candidate bone-substitute and dental-implant material in the future.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Teste de Materiais / Implantes Dentários / Substitutos Ósseos / Nanotubos de Carbono / Nanocompostos Limite: Animals Idioma: En Ano de publicação: 2007 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Teste de Materiais / Implantes Dentários / Substitutos Ósseos / Nanotubos de Carbono / Nanocompostos Limite: Animals Idioma: En Ano de publicação: 2007 Tipo de documento: Article