One-step synthesis of hypoxanthine from glycinamide and diformylurea.
Chem Biodivers
; 1(1): 106-11, 2004 Jan.
Article
em En
| MEDLINE
| ID: mdl-17191778
ABSTRACT
Because of their easy availability and their relative chemical stability, urea, formic acid, and glycine might have played a role in the assembly process of nucleobases. In this paper, a short reaction path is described to prepare hypoxanthine starting from the above mentioned precursors. The formation of hypoxanthine has been verified by high-resolution mass spectrometry with the 15N-labelled urea as starting material, and HPLC analysis. The yield of this condensation reaction has been determined spectrophotometrically.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ureia
/
Hipoxantina
/
Formiatos
/
Glicina
Idioma:
En
Ano de publicação:
2004
Tipo de documento:
Article