Ulnar nerve repair by end-to-side neurorrhaphy on the median nerve with interposition of a vein: an experimental study.
Microsurgery
; 27(1): 27-31, 2007.
Article
em En
| MEDLINE
| ID: mdl-17205574
ABSTRACT
Our study used a rat animal model to verify that Schwann cell migration, collateral axonal sprouting, and regeneration were not hindered by interposition of a 10-mm vein segment between the distal stump of the transected ulnar nerve and the donor median nerve in end-to-side reconstruction. Reconstructed nerves were withdrawn at 7, 14, 30, and 60 days after surgery, then analyzed by confocal laser microscopy after immunolabeling with anti-neurofilament-200 kD (an axonal marker) and anti-S100 (a glial marker) antibodies. Results are reported at 7, 14, 30, and 60 days after surgery. Our observations indicate that chemotactic factors that stimulate end-to-side nerve regeneration can exert their action at this distance. These findings suggest a possible clinical application for this surgical technique in cases when the severed nerve stump is far from the potential donor nerve.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nervo Ulnar
/
Nervo Mediano
Limite:
Animals
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article