Comment on "A common genetic variant is associated with adult and childhood obesity".
Science
; 315(5809): 187; author reply 187, 2007 Jan 12.
Article
em En
| MEDLINE
| ID: mdl-17218510
ABSTRACT
Contrary to the findings of Herbert et al. (Reports, 14 April 2006, p. 279), homozygous carriers of the C allele of the rs7566605 variant near the INSIG2 gene did not exhibit a significantly increased risk for obesity in a large population-based cross-sectional German study. A subgroup analysis, however, revealed that this allele significantly increased the risk for obesity in already overweight individuals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Variação Genética
/
Índice de Massa Corporal
/
Polimorfismo de Nucleotídeo Único
/
Peptídeos e Proteínas de Sinalização Intracelular
/
Proteínas de Membrana
/
Obesidade
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article