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Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides.
Chan, Chuen; Borthwick, Alan D; Brown, David; Burns-Kurtis, Cynthia L; Campbell, Matthew; Chaudry, Laiq; Chung, Chun-wa; Convery, Máire A; Hamblin, J Nicole; Johnstone, Lisa; Kelly, Henry A; Kleanthous, Savvas; Patikis, Angela; Patel, Champa; Pateman, Anthony J; Senger, Stefan; Shah, Gita P; Toomey, John R; Watson, Nigel S; Weston, Helen E; Whitworth, Caroline; Young, Robert J; Zhou, Ping.
Afiliação
  • Chan C; CVU UK Medicinal Chemistry Department, GlaxoSmithKline Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom. chuen.8chan@gsk.com
J Med Chem ; 50(7): 1546-57, 2007 Apr 05.
Article em En | MEDLINE | ID: mdl-17338508
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Sulfonamidas / Fator Xa / Morfolinas / Inibidores do Fator Xa / Anticoagulantes Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2007 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolidinas / Sulfonamidas / Fator Xa / Morfolinas / Inibidores do Fator Xa / Anticoagulantes Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2007 Tipo de documento: Article