Non-fouling microfluidic chip produced by radio frequency tetraglyme plasma deposition.
Lab Chip
; 7(4): 523-5, 2007 Apr.
Article
em En
| MEDLINE
| ID: mdl-17389972
ABSTRACT
This Technical Note presents the direct surface modification of a glass/PTFE hybrid microfluidic chip, via radio frequency glow discharge plasma polymerisation of tetraethlylene glycol dimethylether (tetraglyme), to produce hydrophilic, non-fouling, PEO-like surfaces. We use several techniques including X-ray photoelectron spectroscopy (XPS), direct enzyme-linked immunosorbent assays (ELISA) and immunofluorescent imaging to investigate the channel coatings. Our results indicate the successful deposition of a PEO-like coating onto microchannel surfaces that has both solution and shelf stability (>3 months) and is capable of preventing fibrinogen adsorption to the microchannel surfaces.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microfluídica
/
Técnicas Analíticas Microfluídicas
/
Etilenoglicóis
Limite:
Humans
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article