Solitary extramedullary plasmacytoma of the canine larynx.
J Small Anim Pract
; 48(5): 288-91, 2007 May.
Article
em En
| MEDLINE
| ID: mdl-17425696
ABSTRACT
An 11-year-old, female, spayed cocker spaniel was presented with dysphonia caused by a solitary laryngeal mass. Excisional biopsy was performed, and a diagnosis of plasmacytoma was made on the basis of histological examination. Further investigations showed no signs of systemic involvement. Coarse fractionated radiation therapy failed to control the tumour. Therapy was successfully instituted with a conventional combination chemotherapy protocol over a period of 14 months. The dog remains disease free 30 months after diagnosis. Most solitary, extramedullary plasmacytomas in dogs arise in the gastrointestinal tract, with fewer reports in other sites. The larynx is an uncommon sight of involvement in any species, and to the authors' knowledge, this is the first report of this tumour type in the canine larynx. In contrast to the therapeutic benefits reported in humans, the combination of surgery and radiation therapy was unsuccessful in this case, although sustained remission was gained following chemotherapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmocitoma
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Neoplasias Laríngeas
/
Doenças do Cão
Tipo de estudo:
Guideline
Limite:
Animals
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article