Penile-preserving surgery for male distal urethral carcinoma.
BJU Int
; 100(1): 82-7, 2007 Jul.
Article
em En
| MEDLINE
| ID: mdl-17488307
ABSTRACT
OBJECTIVE:
To evaluate medium-term outcome data from patients with distal urethral cancers treated with penile-preserving surgery. PATIENTS ANDMETHODS:
We analysed prospectively 18 consecutive men referred for the management of urethral carcinoma. All had a specialist review in a supra-regional multidisciplinary team meeting, where the histology findings were reviewed by one pathology consultant. Tumours were staged according to the Tumour-Node-Metastasis classification and the patients offered penile-preserving surgery when tumours were limited to the glanular or penile urethra.RESULTS:
All 18 patients were suitable for penile-preserving surgery; the procedures were three hypospadias formation with or without topical chemotherapy; four buccal mucosa urethroplasty; three glansectomy and reconstruction; six glansectomy, distal corporectomy, reconstruction and hypospadias formation; two urethrectomy with or with no excision of adjacent tunica albuginea. The mean (median, range) follow-up was 26 (20.5, 9-58) months. There were no local recurrences; four patients with regional nodal disease progressed and of these, two died from metastatic disease, and one died from an unrelated condition.CONCLUSION:
Medium-term data show that penile-preserving surgery is a feasible treatment for men with distal urethral carcinoma, providing excellent local control without prejudicing survival; a longer follow-up is needed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pênis
/
Procedimentos Cirúrgicos Urológicos Masculinos
/
Neoplasias Uretrais
/
Carcinoma de Células Escamosas
Tipo de estudo:
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Aged80
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article