Clinical characteristics and outcome of Candida keratitis.
Am J Ophthalmol
; 143(6): 1043-1045, 2007 Jun.
Article
em En
| MEDLINE
| ID: mdl-17524775
ABSTRACT
PURPOSE:
To characterize the clinical features and therapeutic outcome of Candida keratitis.DESIGN:
Retrospective, observational case series.METHODS:
We reviewed 26 patients treated for Candida keratitis, including two with recurrent keratitis and one with bilateral infection.RESULTS:
Of 29 keratitis episodes resulting from Candida albicans (n = 20) or Candida parapsilosis (n = 9), 16 (55%) complicated chronic ocular surface disease, and nine (31%) followed previous keratoplasty. Only two were clinically suspected to have keratomycosis at initial presentation, and 21 (72%) used antibacterial therapy before corneal scrapings. Reconstructive keratoplasty occurred more often in previously grafted eyes (P = .03). Visual outcome was 20/60 or better in six (100%) medically treated eyes with good presenting visual acuity but in only five eyes (24%) with worse initial vision (P = .002).CONCLUSIONS:
Candida keratitis is an opportunistic infection of a compromised cornea that often is misdiagnosed initially and, despite antifungal therapy, occasionally requires corneal grafting.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Candidíase
/
Infecções Oculares Fúngicas
/
Úlcera da Córnea
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article