Report of a variant t(1;15;17)(p36;q22;q21.1) in a patient with acute promyelocytic leukemia.
Cancer Genet Cytogenet
; 57(2): 201-7, 1991 Dec.
Article
em En
| MEDLINE
| ID: mdl-1756499
ABSTRACT
Chromosome analysis of bone marrow aspirate from a 46-year-old man with acute promyelocytic leukemia (APL) revealed a variant translocation, 46,XY,t(115;17)(p36;q22;q21.1). The breakpoints in chromosomes 15 and 17 appear to be the same as those in the more common translocation, t(15;17), associated with APL. The common translocation has been reported in up to 80% of cases of APL. Seventeen cases with variant translocations have been reported involving 15 alone, 17 alone, or 15, 17, and some other chromosome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucemia Promielocítica Aguda
/
Aberrações Cromossômicas
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article