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In vivo efficacy of moxifloxacin compared with cloxacillin and vancomycin in a Staphylococcus aureus rabbit arthritis experimental model.
Grossi, Olivier; Caillon, Jocelyne; Arvieux, Cedric; Jacqueline, Cedric; Bugnon, Denis; Potel, Gilles; Hamel, Antoine.
Afiliação
  • Grossi O; Université de Nantes, Nantes Atlantique Universités, Thérapeutiques Cliniques et Expérimentales des Infections, EA3826, UFR Médecine, Nantes, France.
Antimicrob Agents Chemother ; 51(9): 3401-3, 2007 Sep.
Article em En | MEDLINE | ID: mdl-17576849
ABSTRACT
We investigated the efficacies of moxifloxacin, cloxacillin, and vancomycin in a rabbit model of Staphylococcus aureus arthritis. No significant difference between therapeutic regimens was observed after a 7-day treatment. Oral moxifloxacin could be a suitable alternative to standard parenteral therapy for S. aureus arthritis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Quinolinas / Infecções Estafilocócicas / Compostos Aza / Vancomicina / Artrite Infecciosa / Cloxacilina / Antibacterianos Limite: Animals Idioma: En Ano de publicação: 2007 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Quinolinas / Infecções Estafilocócicas / Compostos Aza / Vancomicina / Artrite Infecciosa / Cloxacilina / Antibacterianos Limite: Animals Idioma: En Ano de publicação: 2007 Tipo de documento: Article