Acute ophthalmoparesis associated with anti-GM1, anti-GD1a, and anti-GD1b antibodies after enterovirus infection in a 6-year-old girl.
J Child Neurol
; 22(4): 432-4, 2007 Apr.
Article
em En
| MEDLINE
| ID: mdl-17621523
ABSTRACT
This article presents a 6-year-old girl who developed acute unilateral third cranial nerve palsy in the absence of any other sign of central nervous system involvement. Raised titers of immunoglobulin M antibodies against GM1, GD1a, and GD1b ganglioside components were demonstrated. Ten days earlier, the girl had experienced acute gastroenteritis with positive specific immunoglobulin M antibodies against enterovirus. The results of all other laboratory tests usually performed for infectious diseases were negative, and neuroradiologic findings were also normal. Oral prednisone was administered for a few days, and the ophthalmoparesis fully resolved within 1 month. Two months later, a second episode of isolated ophthalmoparesis occurred, again associated with a positive immunoglobulin M reaction against GM1, GD1a, and GD1b antigens. This report discusses the relationship between acute isolated ophthalmoparesis and antiganglioside antibodies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oftalmoplegia
/
Infecções por Enterovirus
/
Gangliosídeos
/
Anticorpos
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Child
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article