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Phase I and pharmacokinetic study of the oral farnesyltransferase inhibitor lonafarnib administered twice daily to pediatric patients with advanced central nervous system tumors using a modified continuous reassessment method: a Pediatric Brain Tumor Consortium Study.
Kieran, Mark W; Packer, Roger J; Onar, Arzu; Blaney, Susan M; Phillips, Peter; Pollack, Ian F; Geyer, J Russell; Gururangan, Sri; Banerjee, Anu; Goldman, Stewart; Turner, Christopher D; Belasco, Jean B; Broniscer, Alberto; Zhu, Yali; Frank, Emily; Kirschmeier, Paul; Statkevich, Paul; Yver, Antoine; Boyett, James M; Kun, Larry E.
Afiliação
  • Kieran MW; Dana-Farber Cancer Institute and Children's Hospital Boston, Boston, MA 02115, USA. mark_Kieran@dfci.Harvard.edu
J Clin Oncol ; 25(21): 3137-43, 2007 Jul 20.
Article em En | MEDLINE | ID: mdl-17634493
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Piridinas / Neoplasias do Sistema Nervoso Central / Inibidores Enzimáticos / Farnesiltranstransferase / Invasividade Neoplásica Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Ano de publicação: 2007 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Piridinas / Neoplasias do Sistema Nervoso Central / Inibidores Enzimáticos / Farnesiltranstransferase / Invasividade Neoplásica Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Idioma: En Ano de publicação: 2007 Tipo de documento: Article