Epstein-Barr virus in an American patient with Burkitt's lymphoma: detection of viral genome in tumor tissue and establishment of a tumor-derived cell line (NAB).
J Natl Cancer Inst
; 56(4): 701-4, 1976 Apr.
Article
em En
| MEDLINE
| ID: mdl-176407
ABSTRACT
Epstein-Barr virus (EBV) DNA (17.7 genome equivalents/cell) was found in tumor tissue from an American patient with Burkitt's lymphoma who had never traveled outside the United States. A lymphoid cell line (NAB) containing the EBV genome was established from tumor tissue from this patient; characteristics of this cell line were described. Previous Burkitt's tumors found in Americans and examined by molecular hybridization were negative for EBV DNA. Our results suggested that EBV is associated with at least some American Burkitt's tumors.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA Viral
/
Linfoma de Burkitt
/
Herpesvirus Humano 4
Tipo de estudo:
Diagnostic_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1976
Tipo de documento:
Article