The effects of an intensive lifestyle modification program on carotid artery intima-media thickness: a randomized trial.
Am J Health Promot
; 21(6): 510-6, 2007.
Article
em En
| MEDLINE
| ID: mdl-17674638
ABSTRACT
PURPOSE:
This study evaluated the effect of the Dr. Dean Ornish Program for Reversing Heart Disease on cardiovascular disease as measured by the intima-media thickness of the common carotid artery and compared this effect to outcomes from patients participating in traditional cardiac rehabilitation.DESIGN:
Randomized clinical trial.SETTING:
Swedish American Health System.SUBJECTS:
Ninety three patients with clinically confirmed coronary artery disease were randomly assigned to the intervention (n = 46) or traditional cardiac rehabilitation (n = 47). INTERVENTION Dr. Dean Ornish Program for Reversing Heart Disease.MEASURES:
Ultrasound of the carotid artery and other cardiovascular risk factors were measured at baseline, 6, and 12 months.ANALYSIS:
Intent-to-treat analysis.RESULTS:
There was no significant reduction in the carotid intima-media thickness of the carotid artery in the Ornish group or the cardiac rehabilitation group. Ornish Program participants had significantly improved dietary habits (p < .001), weight (p < .001), and body mass index (p < .001) as compared with the rehabilitation group. The decrease in the number of patients with angina from baseline to 12 months was 44% in Ornish and 12% in cardiac rehabilitation.CONCLUSIONS:
The Ornish Program appears to causes improvements in cardiovascular risk factors but does not appear to change the atherosclerotic process as it affects the carotid artery.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
/
Endotélio Vascular
/
Artérias Carótidas
/
Estilo de Vida
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article