Surface conductivity of biological macromolecules measured by nanopipette dielectrophoresis.
Phys Rev Lett
; 98(19): 198102, 2007 May 11.
Article
em En
| MEDLINE
| ID: mdl-17677664
ABSTRACT
We report the measurement of the surface conductivity of biological macromolecules by dielectrophoretic trapping at the tip of a glass nanopipet. We find that the threshold voltage for trapping is a function of salt concentration and can be directly linked to the effective conductivity of the biomolecule and its solvation shell. The surface conductivities obtained for 20-mer single-stranded DNA, 40-mer double-stranded DNA, and yellow fluorescent protein are 7.9+/-1.9 nS, 5.3+/-0.7 nS, and 21.5+/-1.6 nS, respectively.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sais
/
Proteínas de Bactérias
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DNA
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DNA de Cadeia Simples
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Condutividade Elétrica
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Proteínas Luminescentes
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article