The star-allele nomenclature: retooling for translational genomics.
Clin Pharmacol Ther
; 82(3): 244-8, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17700589
ABSTRACT
The star-allele nomenclature is the result of efforts to standardize genetic polymorphism annotation for the cytochrome P450 genes. As clinical pharmacogenetic testing becomes widespread, it is important that this system effectively communicate a patient's genotype and predicted clinical phenotype. As genomics research expands, it is equally important that the system remain a valuable tool for the wider community of genetic researchers to exploit our ever-improving ability to catalog variability in the human genome.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biossíntese de Proteínas
/
Genômica
/
Alelos
/
Terminologia como Assunto
Limite:
Humans
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article