Staging of esophageal cancer by EUS: staging accuracy revisited.
Gastrointest Endosc
; 66(3): 475-82, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17725937
ABSTRACT
BACKGROUND:
EUS plays an important role in the preoperative staging of esophageal cancer. Recent data have called into question the staging accuracy of EUS, particularly in patients with early disease.OBJECTIVE:
Our goals were to assess our institution's EUS staging accuracy by experienced endosonographers in a contemporary cohort of patients encompassing a wide range of disease stages and to assess staging accuracy after dilation of malignant strictures.DESIGN:
Retrospective data review.SETTING:
Single tertiary care center. PATIENTS ANDINTERVENTIONS:
A total of 42 patients with esophageal cancer undergoing preoperative EUS staging without neoadjuvant chemoradiotherapy between December 1999 and December 2004 were evaluated. MAIN OUTCOME MEASUREMENTS EUS T and N stage sensitivity, specificity, positive predictive value, negative predictive value, and accuracy.RESULTS:
EUS accurately predicted T stage in 76% of cases and N stage in 89% of cases. Staging accuracy for T3 versus T1 and T2 disease and for N0 versus N1 disease was not significantly different. In 11 cases, malignant strictures required dilation, with 6 tumors being passable post dilation. Post dilation, T staging accuracy was 80% in impassable tumors and 100% in passable tumors, and N staging accuracy was 100% in the passable tumors.LIMITATIONS:
Relatively small number of patients.CONCLUSIONS:
EUS accurately predicts T and N stage in patients with a range of disease stages. EUS provides good staging accuracy after dilation of malignant strictures regardless of whether full tumor traversal post dilation is possible.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Esofágicas
/
Carcinoma de Células Escamosas
/
Adenocarcinoma
/
Carcinoma Neuroendócrino
/
Endossonografia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
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Male
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article