Induction of late graft-versus-host disease in a patient post-allogeneic stem cell transplantation by progesterone in conjunction with donor lymphocyte infusion.
Leuk Res
; 32(3): 501-3, 2008 Mar.
Article
em En
| MEDLINE
| ID: mdl-17727947
ABSTRACT
Patients after stem cell transplantation (SCT), often develop graft-versus-host disease (GVHD) which, although potentially dangerous, is associated with the beneficial graft-versus-leukemia (GVL) effect. Where there is high risk of disease recurrence, donor lymphocyte infusions (DLI) are given to provide long-term disease control. We present a patient treated with DLI 4 years post-SCT, who developed acute GVHD after administration of progesterone to induce menstruation. This rare allergic reaction warrants further investigation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Progesterona
/
Transfusão de Linfócitos
/
Transplante de Células-Tronco
/
Doença Enxerto-Hospedeiro
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article