Coenzyme biosynthesis: enzyme mechanism, structure and inhibition.

Scott, Duncan E; Ciulli, Alessio; Abell, Chris

Scott, Duncan E; Ciulli, Alessio; Abell, Chris.

Afiliação

Scott DE; University Chemical Laboratory, Lensfield Road, Cambridge, CB2 1EW, UK.

Nat Prod Rep ; 24(5): 1009-26, 2007 Oct.

Article em En | MEDLINE | ID: mdl-17898895

ABSTRACT

ABSTRACT

This review highlights five key reactions in vitamin biosynthesis and in particular focuses on their mechanisms and inhibition and insights from structural studies. Each of the enzymes has the potential to be a target for novel antimicrobial agents.

Assuntos

Anti-Infecciosos; Coenzimas; Enzimas; Vitaminas; Coenzimas/biossíntese; Coenzimas/química; Coenzimas/metabolismo; Enzimas/efeitos dos fármacos; Enzimas/metabolismo; Estrutura Molecular; Vitaminas/biossíntese; Vitaminas/química; Vitaminas/metabolismo

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitaminas / Coenzimas / Enzimas / Anti-Infecciosos Idioma: En Ano de publicação: 2007 Tipo de documento: Article

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