Histopathologic evaluation of the peritoneum exposed to heat shock: experimental study in rats.
Acta Cir Bras
; 22(5): 342-50, 2007.
Article
em En
| MEDLINE
| ID: mdl-17923953
ABSTRACT
PURPOSE:
To evaluate histopathologic alterations of the peritoneum exposed to heat shock.METHODS:
Sixty rats were randomly distributed into 6 groups Heat Shock (HS), High Temperature (HT), Body Temperature (BT), Temperature 0oC (TZ), Sham (SH) and Control (CG) with 10 animals each. The peritoneal cavity of animals from groups HS, HT, BT and TZ was irrigated with NaCl solution 0.9% at temperatures 50 degrees C, 0 degrees C, 50 degrees C, 37 degrees C and 0 degrees C, respectively. For animals from group SH, the procedures were simulated and those from group CG, laparotomy and biopsies were conducted. Twenty-four hours later, biopsies of the peritoneum for exams under light and electronic microscopy were performed.RESULTS:
Edema was found in groups HS 80%, HT 60%, BT 30% TZ 70%, SH 40% and CG 30%. Vascular congestion was found in groups HS 20%, HT 30%, BT 10% and TZ 20%. Erythrocyte extravasation was found in groups HT 60% and SH 10%. Mesothelium destruction was found in 100% of specimens from groups HS, HT, BT, TZ, SH and CG 90%. Necrosis was found in groups HS 30%, HT 20% and BT 10%. The mean peritoneal thickness ranged from 42.26 microm (TZ) to 26.42 microm (CG).CONCLUSION:
The heat shock caused no deaths, but promoted significant peritoneal edema without affecting the other histopathologic indicatives.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peritônio
/
Lavagem Peritoneal
/
Cloreto de Sódio
/
Resposta ao Choque Térmico
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article