The effect of aluminum ions and sorbitol on collagen and skin: a thermally stimulated current spectroscopy study.
J Biomed Mater Res
; 25(11): 1339-46, 1991 Nov.
Article
em En
| MEDLINE
| ID: mdl-1797806
ABSTRACT
The influence of aluminum ions introduced either directly or with sorbitol, in collagen and skin, has been investigated by Thermally Stimulated Current/TSC spectroscopy. The intramolecular mobility of collagen has been found to be significantly reduced by aluminum ions. The substitution of water molecules by aluminum ions on intramolecular hydrophilic sites is suggested to be responsible for this evolution. The presence of sorbitol minimizes this effect. The intermolecular mobility of collagen is decreased upon introduction of aluminum ions in presence of sorbitol. This result can be explained by the interaction of sorbitol-aluminum entities with the telopeptidic regions of collagen molecules. In skin samples, the intra- and intermolecular mobilities are restored due to the combined actions of sorbitol and noncollagenous proteins and other macromolecules.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Sorbitol
/
Colágeno
/
Alumínio
Limite:
Animals
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article