Pigmented ganglioneuroblastoma: relation of melanin and lipofuscin to schwannomas and other tumors of neural crest origin.
J Neuropathol Exp Neurol
; 35(4): 393-403, 1976 Jul.
Article
em En
| MEDLINE
| ID: mdl-180265
ABSTRACT
An unusual case of ganglioneuroblastoma containing melanin is presented. Electron microscopy revealed various stages of development of melanosomes in neoplastic cells of Schwann, the first direct demonstration in human material that these cells are malanogenic. The frequent occurrence of neuromelanin in autonomic ganglia and in ganglioneuromas is interpreted as the presence of altered lipofuscin. Review of ultrastructural and other observations indicates a relation between various pigmented tumors, the cell of Schwann, and other cells arising from the neural crest.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Sistema Nervoso Periférico
/
Pigmentos Biológicos
/
Ganglioneuroma
/
Lipofuscina
/
Melaninas
/
Neurilemoma
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1976
Tipo de documento:
Article