Cortical excitability in Duchenne muscular dystrophy.
Clin Neurophysiol
; 119(2): 459-65, 2008 Feb.
Article
em En
| MEDLINE
| ID: mdl-18053763
ABSTRACT
OBJECTIVE:
To investigate the probable cortical excitability changes in DMD by electrophysiological means.METHODS:
Sixteen cases with DMD, 10 age-matched control children (CC) and 10 healthy adult volunteers (AC) were studied with a transcranial magnetic stimulation (TMS) test battery composed of central conduction time, cortical silent period and paired TMS paradigm.RESULTS:
There were no significant differences between DMD and CC groups except for lower amplitude motor responses in DMD cases. These two groups showed a similar pattern of excitability with less short interval intracortical inhibitions and shorter silent period durations as compared to the AC subjects.CONCLUSIONS:
The electrophysiological tests performed in our DMD patients did not reveal abnormalities caused particularly by the disorder.SIGNIFICANCE:
TMS excitability studies performed in DMD boys may not provide findings other than those related to the developmental age.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Cerebral
/
Potencial Evocado Motor
/
Distrofia Muscular de Duchenne
Limite:
Adolescent
/
Adult
/
Child
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article