[Parathyroid and bone. Evidence and perspective of parathyroid therapy for patients with osteoporosis].
Clin Calcium
; 17(12): 1888-94, 2007 Dec.
Article
em Ja
| MEDLINE
| ID: mdl-18057665
ABSTRACT
Parathyroid hormone (PTH) is a new management option for patients with osteoporosis. As an anabolic agent that affects bone remodeling and modeling, a novel approach to reducing fracture risk could be considered for patients with severe conditions. A number of trials have shown that increases in spine and hip bone mineral density (BMD), and reduction of fracture risk in postmenopausal women. Although the combination of PTH and alendronate does not seem to be additive, PTH followed by alendronate would yield maximum increase in BMD. Treatment with PTH can change the course of osteoporosis by directly stimulating formation of new bone, and its application should be explored in daily clinical practice.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hormônio Paratireóideo
/
Osteoporose Pós-Menopausa
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
Idioma:
Ja
Ano de publicação:
2007
Tipo de documento:
Article