Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate.
FEMS Microbiol Lett
; 279(1): 77-82, 2008 Feb.
Article
em En
| MEDLINE
| ID: mdl-18081842
ABSTRACT
Homotaurine (3-aminopropanesulfonate), free or derivatized, is in widespread pharmaceutical and laboratory use. Studies with enrichment cultures indicated that the compound is degradable as a sole source of carbon or as a sole source of nitrogen for bacterial growth. A pure culture of Burkholderia sp. was isolated which assimilated the amino group from homotaurine in a glucose-salts medium, and which released an organosulfonate, 3-sulfopropanoate, into the medium stoichiometrically. The deamination involved an inducible 2-oxoglutarate-dependent aminotransferase to yield glutamate, and 3-sulfopropanal. Release of the amino group was attributed to the measured NADP-coupled glutamate dehydrogenase.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Propionatos
/
Taurina
/
Burkholderia
/
Nitrogênio
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article