[Prevention of early-onset group B streptococcus neonatal diseases. The 2005 experience of the Lille University Health Center]. / Prévention des infections bactériennes néonatales précoces à streptocoque B. L'expérience du CHRU de Lille en 2005.
J Gynecol Obstet Biol Reprod (Paris)
; 37(4): 392-9, 2008 Jun.
Article
em Fr
| MEDLINE
| ID: mdl-18243572
ABSTRACT
OBJECTIVES:
To study the efficiency of the official recommendations on the prevention of group B streptococcus and the impact of this strategy. MATERIALS ANDMETHODS:
A prospective study was realized in 2005. All infants who were live-born at the Jeanne-de-Flandre hospital (Lille, France) and their mothers were included in the study. Data concerned both pregnancy (vaginal screening, intrapartum antibiotic) and newborn (safe, colonization and early-onset neonatal bacterial disease).RESULTS:
Our study included 4353 mother-newborn couples. Vaginal screening was performed on 92% of the women included in the study. Prevalence of vaginal group B streptococcus in screened women was 7%. Perpartum antibioprophylaxia of group B streptococcus was achieved in 12% of the women included in the study. Group B streptococcus was associated to 60% of probable and certain early-onset bacterial neonatal diseases, with an incidence of 9/1000 births. Exposition to antenatal antibiotherapy multiplied by two the risk of ampicillin resistant Gram-negative bacilli (RR=2 [1.1-3.8]).CONCLUSION:
Recommendations were well followed, but in our health center group, B streptococcus was the main bacteria responsible for early-onset bacterial neonatal diseases. Because of the risk of germ selection, a more targeted antibioprophylaxia has to be preferred.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações Infecciosas na Gravidez
/
Infecções Estreptocócicas
/
Transmissão Vertical de Doenças Infecciosas
/
Antibioticoprofilaxia
/
Doenças do Recém-Nascido
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Adult
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Female
/
Humans
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Newborn
/
Pregnancy
País/Região como assunto:
Europa
Idioma:
Fr
Ano de publicação:
2008
Tipo de documento:
Article