Cytokine inhibition of DNA synthesis: effect on cyclic adenosine monophosphate in lymphocytes.
Science
; 193(4259): 1260-2, 1976 Sep 24.
Article
em En
| MEDLINE
| ID: mdl-183266
ABSTRACT
A greater than twofold increase in intracellular adenosine 3',5'-monophosphate (cyclic AMP) inhibited DNA synthesis, in stimulated rat lymphocytes. A two- to fourfold rise of intracellular cyclic AMP, starting at 16 hours, was produced by purified inhibitor od DNA synthesis added to such cells either at 0 or 16 hours, in close association with the initiation of DNA synthesis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Linfócitos
/
Linfocinas
/
AMP Cíclico
Limite:
Animals
Idioma:
En
Ano de publicação:
1976
Tipo de documento:
Article