[Studies on absorption kinetics of paeonol and paeonol-beta-CD in rat's intestines].
Zhongguo Zhong Yao Za Zhi
; 33(1): 35-7, 2008 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-18338616
ABSTRACT
To explore the absorption mechanism of paeonol-beta-CD from various intestinal segments and offer biopharmaceutics data for paeonol new dosage form. The absorption kinetics and permeability rate consatants were investigated by the in situ perfusing method in rats. The absorption of the drug conforms to the firt-order kinetics and passive transport mechanism . The results indicate that paeonol-beta-CD absorption mechanism wasn't change.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetofenonas
/
Absorção Intestinal
/
Mucosa Intestinal
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2008
Tipo de documento:
Article