The morphology and location of atrial specific granules and the demonstration of atrial natriuretic factor in porcine, lapine and bovine heart by immunoelectronmicroscopy.
Vet Res Commun
; 15(5): 335-40, 1991.
Article
em En
| MEDLINE
| ID: mdl-1837636
ABSTRACT
The atrial specific granules (ASGs) were studied in samples collected from the right and left auricles of conventionally slaughtered cows (10), pigs (16) and rabbits (8). In addition, the presence of atrial natriuretic factor (ANF) was detected by immunocytochemistry. Mature ASGs, characterized by the presence of highly osmiophilic and electron-dense material surrounded by a membrane, were present in all atrial myoendocrine cells and their diameters ranged from 100 to 470 nm in pigs, from 100 to 235 nm in cattle, and from 125 to 275 nm in rabbits. Immunoelectronmicroscopical studies revealed the presence of ANF in the ASGs of pigs and cattle, whereas anti-ANF polyclonal serum failed to detect any significative reaction in lapine ASGs. The ultrastructural features of the ASGs of pigs, cattle and rabbits described may be useful in comparing the morphological picture of several cardiac endocrine pathological conditions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Coelhos
/
Suínos
/
Bovinos
/
Fator Natriurético Atrial
/
Miocárdio
Limite:
Animals
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article