Anti-HIV-1 protease triterpenoids from Stauntonia obovatifoliola Hayata subsp. intermedia.
Phytochemistry
; 69(9): 1875-9, 2008 Jun.
Article
em En
| MEDLINE
| ID: mdl-18433808
ABSTRACT
Three triterpenoids, 16beta-hydroxy-2,3-seco-lup-20(29)-ene-2,3-dioic acid (1), 3beta,21beta,24-trihydroxy-30-noroleana-12,20(29)-dien-28-oic acid (2) and 16beta-hydroxylupane-1,20(29)-dien-3-one (3), along with eleven known triterpenes were isolated from stems of Stauntonia obovatifoliola Hayata subsp. intermedia (Y.C. Wu) T. Chen. Their structures were determined by analysis of HR-EI/FAB-MS and 1D and 2D NMR spectroscopic data and comparison with those in the literature. Ten of the compounds showed inhibitory activity against HIV-1 protease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Inibidores da Protease de HIV
/
Gleiquênias
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article