CoPub: a literature-based keyword enrichment tool for microarray data analysis.
Nucleic Acids Res
; 36(Web Server issue): W406-10, 2008 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-18442992
ABSTRACT
Medline is a rich information source, from which links between genes and keywords describing biological processes, pathways, drugs, pathologies and diseases can be extracted. We developed a publicly available tool called CoPub that uses the information in the Medline database for the biological interpretation of microarray data. CoPub allows batch input of multiple human, mouse or rat genes and produces lists of keywords from several biomedical thesauri that are significantly correlated with the set of input genes. These lists link to Medline abstracts in which the co-occurring input genes and correlated keywords are highlighted. Furthermore, CoPub can graphically visualize differentially expressed genes and over-represented keywords in a network, providing detailed insight in the relationships between genes and keywords, and revealing the most influential genes as highly connected hubs. CoPub is freely accessible at http//services.nbic.nl/cgi-bin/copub/CoPub.pl.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
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MEDLINE
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Análise de Sequência com Séries de Oligonucleotídeos
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Perfilação da Expressão Gênica
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article