Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones.
Bioorg Med Chem Lett
; 18(18): 5087-90, 2008 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-18752951
ABSTRACT
A novel series of bacterial topoisomerase (3-aminoquinazolinediones) inhibitors are described. The side-chain SAR against Gram-positive and Gram-negative organisms as well as DNA gyrase activity is reported.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Quinazolinonas
/
Inibidores da Topoisomerase II
/
Bactérias Gram-Negativas
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Bactérias Gram-Positivas
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Antibacterianos
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article