Synthesis of a photoresponsive alpha-dideoxyuridine triphosphate derivative.
Nucleic Acids Symp Ser (Oxf)
; (52): 293-4, 2008.
Article
em En
| MEDLINE
| ID: mdl-18776369
The synthesis of a photoresponsive alpha-5-cyanovinyl- 2',3'-dideoxyuridine-5'-triphosphate (alpha dd(C)UTP) is described. A one-pot enzymatic synthesis of photoresponsive alpha-5-cyanovinyl-2',3'-dideoxyuridine (alpha dd(C)U) labeled ODNs with terminal deoxynucleotideyl transferase (TdT) would be a powerful tool for the development of modified long-chain DNA and branched DNA unable to be prepared by DNA synthesizer or enzymatic ligation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nucleotídeos de Uracila
/
Uridina Trifosfato
/
Didesoxinucleotídeos
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article