Nitrous oxide vibrational energy relaxation is a probe of interfacial water in lipid bilayers.
J Phys Chem B
; 112(40): 12776-82, 2008 Oct 09.
Article
em En
| MEDLINE
| ID: mdl-18793010
ABSTRACT
Ultrafast infrared spectroscopy of N 2O is shown to be a sensitive probe of hydrophobic and aqueous sites in lipid bilayers. Distinct rates of VER of the nu 3 antisymmetric stretching mode of N 2O can be distinguished for N 2O solvated in the acyl tail, interfacial water, and bulk water regions of hydrated dioleoylphosphatidylcholine (DOPC) bilayers. The lifetime of the interfacial N 2O population is hydration-dependent. This effect is attributed to changes in the density of intermolecular states resonant with the nu 3 band ( approximately 2230 cm (-1)) resulting from oriented interfacial water molecules near the lipid phosphate. Thus, the N 2O VER rate becomes a novel and experimentally convenient tool for reporting on the structure and dynamics of interfacial water in lipids and, potentially, in other biological systems.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vibração
/
Água
/
Sondas Moleculares
/
Bicamadas Lipídicas
/
Óxido Nitroso
Idioma:
En
Ano de publicação:
2008
Tipo de documento:
Article