[Short stature in chronic kidney disease: physiopathology and treatment with growth hormone]. / Baixa estatura na doença renal crônica: fisiopatologia e tratamento com hormônio de crescimento.
Arq Bras Endocrinol Metabol
; 52(5): 783-91, 2008 Jul.
Article
em Pt
| MEDLINE
| ID: mdl-18797585
ABSTRACT
Growth failure is frequent and a clinically important issue in children with chronic kidney disease (CKD). Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH)--insulin-like growth factor 1 (IGF-1) axis, malnutrition, acidosis, renal bone disease and glucocorticoid associated treatment. The management of growth failure in children with CKD is complicated by the presence of other-disease related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, this therapy is still underutilized. This review shows the impact, the causes and the treatment of growth failure in children with CKD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hormônio do Crescimento Humano
/
Transtornos do Crescimento
/
Falência Renal Crônica
Limite:
Humans
Idioma:
Pt
Ano de publicação:
2008
Tipo de documento:
Article