[Treatment of normal pressure glaucoma with a serotonin S2 receptor antagonist, naftidrofuryl (praxilen)]. / Le traitement du glaucome à pression normale avec un antagoniste des recepteurs S2 de la sérotonine, le naftidrofuryl (praxilen).
Klin Monbl Augenheilkd
; 198(5): 332-4, 1991 May.
Article
em Fr
| MEDLINE
| ID: mdl-1886349
ABSTRACT
35 normal tension glaucoma patients were followed during 8 to 11 month. 12 patients received 2 x 200 mg/day Naftidrofuryl, a serotonine S2 receptor antagonist. As controles, another 23 patients were followed without treatment. The treated group, compared with the 23 non treated patients showed a significant increase in visual acuity (p = 0.001), a significant increase of the MS (p = 0.03), and a non significant decrease of the MD and CLV on the Octopus visual field (p, NS). The physiology and physiopathology of serotonine and S2 receptor antagonist are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antagonistas da Serotonina
/
Glaucoma
/
Pressão Intraocular
/
Nafronil
Tipo de estudo:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
Fr
Ano de publicação:
1991
Tipo de documento:
Article