Dietary marine-derived tocopherol has a higher biological availability in mice relative to alpha-tocopherol.
Lipids
; 44(2): 133-43, 2009 Feb.
Article
em En
| MEDLINE
| ID: mdl-18989718
ABSTRACT
The biologic availability of two kinds of tocomonoenols, marine-derived tocopherol (MDT) and alpha-tocomonoenol, was investigated in ICR mice. Vitamin E-deficient ICR mice were fed MDT and alpha-tocomonoenol together with alpha-tocopherol, beta-tocopherol, gamma-tocopherol, and delta-tocopherol, and storage in liver, spleen, lung, and brain was quantified using reverse-phase high-performance liquid chromatography. The vitamin E relative biologic availability (VE-RBA) in liver was 100 for alpha-tocopherol, 26 +/- 3 for beta-tocopherol, 4 +/- 2 for gamma-tocopherol, not detected for delta-tocopherol, 49 +/- 6 for MDT, and 30 +/- 7 for alpha-tocomonoenol. The VE-RBA in brain was 100 for alpha-tocopherol, 5 +/- 2 for beta-tocopherol, not detected for gamma-tocopherol and delta-tocopherol, 8 +/- 1 for MDT, and 4 +/- 1 for alpha-tocomonoenol. Tocopherols and tocomonoenols did not accumulate in the spleen or lung. MDT and alpha-tocomonoenol had high VE-RBA values. The VE-RBA value for MDT was much higher than that for beta-tocopherol.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tocoferóis
/
Alfa-Tocoferol
Limite:
Animals
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article