[Preparation of fractions and characteristic of neutrophilokines complex induced by Yersinia pestis EV].
Zh Mikrobiol Epidemiol Immunobiol
; (5): 65-9, 2008.
Article
em Ru
| MEDLINE
| ID: mdl-19006834
ABSTRACT
Biochemical and immunobiologic characteristics of fractions of neutrophilokines during primary and secondary immune response against plague infection are presented. Fractions were obtained using gel chromatography from neutrophilokines complex induced by vaccine strain of Yersinia pestis. It was revealed that fractions of neutrophilokines regulate IL-2 synthesis by Th1-helpers, IL-4 and IL-5 synthesis by Th2-helpers and also expression of IL-2 receptors by immunocompetent cells. Helper effect of neutrophilokines' fractions was more pronounced during secondary immune response.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peste
/
Yersinia pestis
/
Citocinas
/
Neutrófilos
Limite:
Animals
Idioma:
Ru
Ano de publicação:
2008
Tipo de documento:
Article