Spectral analysis of intracardiac electrograms during induced and spontaneous ventricular fibrillation in humans.
Europace
; 11(3): 328-31, 2009 Mar.
Article
em En
| MEDLINE
| ID: mdl-19109363
ABSTRACT
AIMS:
Very limited data are available on the differences between spontaneous and induced episodes of ventricular fibrillation (VF) in humans. The aim of the study was to compare the spectral characteristics of the electrical signal recorded by an implantable cardioverter defibrillator (ICD) during both types of episodes. METHODS ANDRESULTS:
Thirteen ICD patients with at least one spontaneous and one induced VF recorded by the device were included in the study. A spectral representation was obtained for the first 3 s of the intracardiac unipolar electrogram during VF. The dominant frequency (f(d)), the peak power at f(d), an organization index (OI), a bandwidth measurement, and an estimate of the correlation with a sinusoidal wave (leakage) were estimated for each episode. The f(d) was higher in induced episodes (4.75 +/- 0.57 vs. 3.95 +/- 0.59 Hz for the spontaneous episodes, P = 0.002), as well as the degree of organization assessed by the OI, bandwidth, and leakage parameters.CONCLUSION:
Clinical and induced VF episodes in humans have different spectral characteristics. Changes in the electrophysiological substrate or in the location of the arrhythmia wavefront at onset could play a role to explain the observed differences.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Ventricular
/
Diagnóstico por Computador
/
Desfibriladores Implantáveis
/
Eletrocardiografia
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article