Effect of timing and duration of a single chest compression pause on short-term survival following prolonged ventricular fibrillation.
Resuscitation
; 80(4): 458-62, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-19185411
ABSTRACT
BACKGROUND:
Pauses during chest compressions are thought to have a detrimental effect on resuscitation outcome. The Guidelines 2005 have recently eliminated the post-defibrillation pause. Previous animal studies have shown that multiple pauses of increasing duration decrease resuscitation success. We investigated the effect of varying the characteristics of a single pause near defibrillation on resuscitation outcome.METHODS:
Part A 48 swine were anesthetized, fibrillated for 7min and randomized. Chest compressions were initiated for 90s followed by defibrillation and then resumption of chest compressions. Four groups were studied-G2000 40s pause beginning 20s before, and ending 20s after defibrillation, A1 a 20s pause just before defibrillation, A2 a 20s pause ending 30s prior to defibrillation, and group A3 a 10s pause ending 30s prior to defibrillation. Part B 12 swine (Group B) were studied with a protocol identical to Part A but with no pause in chest compressions. Primary endpoint was survival to 4h.RESULTS:
The survival rate was significantly higher for groups A1, A2, A3, and B (5/12, 7/12, 5/12, and 5/12 survived) than for the G2000 group (0/12, p<0.05). Survival did not differ significantly among groups A1, A2, A3, and B.CONCLUSIONS:
These results suggest that the Guidelines 2005 recommendation to omit the post-shock pulse check and immediately resume chest compressions may be an important resuscitation protocol change. However, these results also suggest that clinical maneuvers further altering a single pre-shock chest compression pause provide no additional benefit.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Ventricular
/
Cardioversão Elétrica
/
Parada Cardíaca
/
Massagem Cardíaca
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article