Bioactive polymers 54. Pharmacological properties of modified neomycin.
J Biomater Appl
; 6(1): 80-8, 1991 Jul.
Article
em En
| MEDLINE
| ID: mdl-1920071
ABSTRACT
Modified neomycin prepared by the ionic coupling on xanthan with an activity of 380 UI/mg was characterized in regard to its in vitro and in vivo release rate and therapeutic action with artificial tear eluent. The dynamic system in vitro release showed that after 4 h, there appears a "zero-order" kinetic. Ophthalmic inserts were prepared from modified neomycin and they are used in treating bacterial conjunctivitis. Sterilization of the conjunctival sac is obtained 12 h after insert administration.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Estafilocócicas
/
Neomicina
/
Conjuntivite Bacteriana
Limite:
Humans
Idioma:
En
Ano de publicação:
1991
Tipo de documento:
Article