Multiple pilomatricomas and gliomatosis cerebri--a new association?
Pediatr Dermatol
; 26(1): 75-8, 2009.
Article
em En
| MEDLINE
| ID: mdl-19250412
ABSTRACT
Pilomatricomas are benign skin tumors originating from hair follicle matrix cells. In 2% to 3.5% of cases they occur in multiplicity and then may be associated with genetic diseases, such as myotonic dystrophy Curschmann-Steinert, familial adenomatous polyposis (Gardner syndrome), and Rubinstein-Taybi syndrome. A 15-year-old boy treated with temozolomide and oxcarbazepine for gliomatosis cerebri with symptomatic epilepsy developed four firm cutaneous nodules on his face and right upper arm in the course of 1 year. All four tumors were excised under local anesthesia. Histological examination confirmed the clinical diagnosis of pilomatricomas. This is the first published case of a patient suffering from gliomatosis cerebri and developing multiple pilomatricomas. Whether this observation represents a new association or is a mere coincidence cannot be clarified at present.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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Neoplasias Encefálicas
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Pilomatrixoma
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Neoplasias Neuroepiteliomatosas
/
Doenças do Cabelo
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Humans
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Male
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article