Association between waste management and cancer in companion animals.
J Vet Intern Med
; 23(3): 564-9, 2009.
Article
em En
| MEDLINE
| ID: mdl-19298612
ABSTRACT
BACKGROUND:
Increased cancer rates have been documented in people residing in areas around Naples characterized by illegal dumping and incineration of waste.HYPOTHESIS:
Risk of cancer in dogs and cats is associated with waste management. ANIMALS Four hundred and fifty-three dogs and cats with cancer and 1,554 cancer-free animals.METHODS:
Hospital-based case-control study in Naples (low danger) and nearby cities having a history of illegal waste dumping (high danger). Odds ratio (OR) between high- and low-danger areas was calculated for all tumors and various malignancies in dogs and cats.RESULTS:
An increased risk for cancer development was identified in dogs but not in cats residing in high-danger areas (OR 1.55; 95% confidence interval 1.18-2.03; P < .01). A 2.39-fold increased risk of lymphoma (P < .01) accounted for the greater tumor frequency in dogs residing in high-danger areas. The risk of mast cell tumor and mammary cancer did not differ in dogs residing in high- or low-danger areas. CONCLUSIONS AND CLINICAL IMPORTANCE Waste emission from illegal dumping sites increases cancer risk in dogs residing in high-danger areas. An increased prevalence of lymphoma has been previously recognized in humans living close to illegal waste dumps. Thus, epidemiological studies of spontaneous tumors in dogs might suggest a role for environmental factors in canine and human carcinogenesis and can predict health hazards for humans.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças do Gato
/
Eliminação de Resíduos
/
Doenças do Cão
/
Poluentes Ambientais
/
Neoplasias
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Animals
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article