Toxic dermatolysis, tissue necrosis and impaired wound healing due to sunitinib treatment leading to forefoot amputation.
Urol Int
; 82(2): 246-8, 2009.
Article
em En
| MEDLINE
| ID: mdl-19322019
ABSTRACT
Innovative treatment strategies in urologic oncology confront the treating physician with a new spectrum of adverse events. With growing understanding of underlying pathomechanisms, we need to identify contraindications against the use of certain antiproliferative drugs. The management of toxicities involves a multidisciplinary approach and thus, the exchange of experience across medical specialties is mandatory. We report a case of fulminant toxic dermatolysis, tissue necrosis and impaired wound healing resulting in the amputation of one forefoot after 6 days of treatment with sunitinib.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pirróis
/
Cicatrização
/
Antepé Humano
/
Síndrome de Stevens-Johnson
/
Inibidores da Angiogênese
/
Cútis Laxa
/
Amputação Cirúrgica
/
Indóis
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article