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Soroprevalência da rubéola na população urbana e rural de Guaratinguetá / [Seroprevalence of rubella in urban and rural populations, Guaratinguetá].

Figueiredo, Cristina A; Afonso, Ana M S; Curti, Suely P; Oliveira, Maria I; Souza, Luisa T M; Sato, Helena Keico; Azevedo, Raymundo S.
Rev Assoc Med Bras (1992) ; 55(2): 117-20, 2009.
Artigo em Português | MEDLINE | ID: mdl-19488643

OBJECTIVE:

To investigate seroprevalence of rubella antibodies in a 15 to 39 year old population in the municipal district of Guaratinguetá.

METHODS:

The 996 samples studied were collected in urban and rural zones, after informed and elucidated consent from men and women stratified by age (15 -39 years). Rubella IgG antibodies were detected by ELISA using the commercial kit Rubenostika IgGII (Organon Teknika THE, Holland). Age groups were stratified in 3 categories: 15-19; 20-29 and 30-39 years of age. Statistical analyses were accomplished with the software MINITAB version 14.0 (Minitab Inc, USA).

RESULTS:

The proportion of seropositives for antibodies of the IgG class were: 92.7.% positive for 15-19 years; 82.4% for 20 to 29 years and 90.7% for 30-39 years, with a significant difference in the seropositive proportions by age group (p <0.001). Variation of intensity of antibody response was calculated and results show a significant difference (p = 0.002) between means of the 3 age groups studied. In relation to rural and urban zone average of the ratio DO/CO for each age group, a significant tendency towards a lower average was observed in the rural zone. The same was true when the seropositive proportions were calculated.

CONCLUSION:

Results showed that the percentage and individuals with antibodies of the IgG class against rubella in the 20-29 year age group was lower than that in the younger and older age groups. Furthermore, the difference between seropositivity in the urban and rural zones discloses susceptibility with a potential for continued circulation of the virus in this zone.