First trial of spatial and temporal fractionations of the delivered dose using synchrotron microbeam radiation therapy.
J Synchrotron Radiat
; 16(Pt 4): 587-90, 2009 Jul.
Article
em En
| MEDLINE
| ID: mdl-19535875
ABSTRACT
The technical feasibility of temporal and spatial fractionations of the radiation dose has been evaluated using synchrotron microbeam radiation therapy for brain tumors in rats. A significant increase in lifespan (216%, p < 0.0001) resulted when three fractions of microbeam irradiation were applied to the tumor through three different ports, orthogonal to each other, at 24 h intervals. However, there were no long-term survivors, and immunohistological studies revealed that 9 L tumors were not entirely ablated.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dosagem Radioterapêutica
/
Neoplasias Encefálicas
/
Síncrotrons
/
Gliossarcoma
Limite:
Animals
Idioma:
En
Ano de publicação:
2009
Tipo de documento:
Article