Factor XIII deficiency as a potential cause of supratentorial haemorrhage after posterior fossa surgery.
Acta Neurochir (Wien)
; 152(3): 529-32, 2010 Mar.
Article
em En
| MEDLINE
| ID: mdl-19557304
ABSTRACT
BACKGROUND:
Postoperative intracranial haemorrhage can be a dramatic event, carrying significant morbidity and mortality. Bleeding at sites remote from the operation area represents a small percentage of haemorrhages whose aetiology remains unclear (Harders et al. Acta Neurochir (Wien) 74(1-2)57-60, 1985).AIM:
We present the case of a 60-year-old patient who underwent posterior fossa craniotomy for the removal of a space-occupying lesion and suffered supratentorial haemorrhage soon after the operation.RESULTS:
A thorough postoperative investigation revealed low levels of factor XIII (FXIII), the factor mainly responsible for fibrin clot stabilisation.CONCLUSION:
We suggest that reduced FXIII activity may be an important but preventable predisposing factor to remote postoperative haemorrhage in neurosurgical patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cerebelo
/
Hemorragia Pós-Operatória
/
Procedimentos Neurocirúrgicos
/
Fossa Craniana Posterior
/
Cistos
/
Deficiência do Fator XIII
Tipo de estudo:
Etiology_studies
Idioma:
En
Ano de publicação:
2010
Tipo de documento:
Article